Endocrine Abstracts

Introduction: Diabetogenic effect limits the use of glucocorticoids (GC).Aim: To evaluate the role of modified HOMA-IR and HOMA-islet indices in different carbohydrate metabolism disorders (CMD) during oral (OGCT) and PULSE (GCPT) glucocorticoid therapy (GCT).Patients and methods: A study including 165 patients with systemic lupus erythematosus (n=53), systemic vasculitis (n=45) and chronic glomerulonephritis (<em...

Introduction: Glucocorticoid therapy (GCT) is one of the risk factors of carbohydrate metabolism disorders (CMD) in patents with systemic inflammatory diseases. CMD development is a concern not only with long-term therapy, but also during intensive short-term glucocorticoid (GC) administration, which can lead to different CMDs, including impaired glucose tolerance (IGT) and diabetes mellitus (DM).Aim: To evaluate the prevalence of CMD after long-term and...